A medical grade laser is one of the best ways of removing those unsightly spider veins from the back of the leg. The ND YAG laser penetrates deeply into the skin targeting the pigment in the blood, causing it to collapse and seal. The vessel is then reabsorbed by the body’s immune system. Results can sometimes be instant and the vein fades away before your eyes or it can take up to 2-3 weeks before disappearing completely.